Stem Cell Research and Regeneration on Cardiology

An innovative therapeutic approach is the use of cell therapy to counteract reverse ventricular remodelling, the substrate of heart failure and arrhythmias following myocardial infarction. Advantageous cell tissue regeneration combines a complex cellular and molecular advent setting that includes stem cell grafting and differentiation, secretion of anti-inflammatory and angiogenic mediators, and proliferation of endogenous cardiac stem cells. Recent therapeutic approaches involve adipose-derived stem cells, heart-derived stem cells, bone marrow-derived mononuclear cells and mesenchymal stem cells, and combinations of cells. Clinical trials using mesenchymal stem cells and cardiac derived stem cells have been shown to be effective in reducing infarct size and improving the contractility of regional walls.

  • Heart repair
  • Gene Therapy for Cardiovascular Disease
  • Endogenous cardiac stem cell
  • Cardiovascular Cell Therapy Research Network
  • Human Engineered Cardiac Tissues
  • Cardiac stem cell therapy

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